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Substituted cathinone
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Substituted cathinone : ウィキペディア英語版
Substituted cathinone

Substituted cathinones, which include some stimulants and entactogens, are derivatives of cathinone. They feature a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon, along with additional substitutions. Cathinone occurs naturally in the plant khat whose leaves are chewed as a recreational drug.〔Colzato LS, Ruiz MJ, van den Wildenberg WP, Hommel B. (Khat use is associated with impaired working memory and cognitive flexibility. ) PLoS One. 2011;6(6):e20602. PMID 21698275. Retrieved 2011-07-17.〕
== Chemical derivatives ==
The derivatives may be produced by substitutions at four locations of the cathinone molecule:
* R1 = hydrogen, or any combination of one or more alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents
* R2 = hydrogen or any alkyl group
* R3 = hydrogen, any alkyl group, or incorporation in a cyclic structure
* R4 = hydrogen, any alkyl group, or incorporation in a cyclic structure
The following table displays notable derivatives that have been reported:


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